منابع مشابه
Pregestational Diabetes Mellitus and Congenital Heart Defects.
2219 Congenital heart defects (CHDs) comprise a wide range of malformations of the heart (ie, atrial and ventricular chambers and septa, and atrioventricular and semilunar valves) and great vessels (ie, the great arteries and systemic and pulmonary veins), reflecting the complexity of developmental processes and potential disturbances in morphogenesis of the cardiovascular system. The first pub...
متن کاملN-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes
BACKGROUND Pregestational diabetes is a major risk factor of congenital heart defects (CHDs). Glutathione is depleted and reactive oxygen species (ROS) production is elevated in diabetes. In the present study, we aimed to examine whether treatment with N-acetylcysteine (NAC), which increases glutathione synthesis and inhibits ROS production, prevents CHDs induced by pregestational diabetes. M...
متن کاملCongenital heart defects in adulthood.
BACKGROUND More than 90% of children with congenital heart defects now survive into adulthood; just a few decades ago, survival was rare, particularly among patients with complex defects. The new population of adults with congenital heart disease presents a special challenge to physicians from all of the involved specialties. METHODS Selective literature review. RESULTS AND CONCLUSION A com...
متن کاملSurgery for Congenital Heart Defects
The third edition of Surgery for Congenital Heart Defects proves to be a userfriendly and instructive resource that is sure to be of great value to many physicians. While the seasoned surgeon might call upon the text as a reference, even the greenest medical student wades comfortably into the depths of the text and feels empowered by the visual feast that awaits. As in the previous editions, me...
متن کاملCongenital Heart Disease Congenital Heart Defects in Europe
Background—This study determines the prevalence of Congenital Heart Defects (CHD), diagnosed prenatally or in infancy, and fetal and perinatal mortality associated with CHD in Europe. Methods and Results—Data were extracted from the European Surveillance of Congenital Anomalies central database for 29 population-based congenital anomaly registries in 16 European countries covering 3.3 million b...
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ژورنال
عنوان ژورنال: American Journal of Preventive Medicine
سال: 2015
ISSN: 0749-3797
DOI: 10.1016/j.amepre.2014.09.002